Does cannabis create thirdhand smoke? Thirdhand Smoke Resource Center Yes, you can donate blood if you smoke or consume cannabis. The recipient of the blood will not get high, another common MYTH. All donors go through the same health Can You Donate Blood if You Smoke Weed? It's Complicated Weedmaps Smoking (or vaping) doesn't affect your ability to donate blood. Help us bust this myth by sharing our post. Can you donate blood if you smoke? Did you know: You CAN donate blood if you use cannabis. If you have any questions about blood donation, please ask us! #DidYouKnowAboutBloodDonation