Peptides are often well tolerated, but they can still cause temporary reactions while the body adapts. Some commonly reported effects include: BPC 157 headaches, nausea, increased appetite TB 500 AOD 9604 Appetite Neutral Fat Loss Process: Weight Management Without Hunger Changes Beverly Hills Rejuvenation Center Peptide side effects no one talks about BPC 157 headaches. TB 500 fatigue. CJC Ipamorelin water retention. Most people quit. But 90% of the time it's the protocol, not the peptide. If youre looking at peptides to boost growth hormone, heres the key difference: Growth hormonereleasing peptides (GHRPs), like Ipamorelin, work by hitting the ghrelin receptor, your bodys hunger Does Ipamorelin Make You Hungry? How to Burn Fat Without the Cravings Florida Surgery & Weight Loss Center The Best Peptides for Weight Loss: GLP 1 and Other Proven Options