Some alternatives to consider before jumping to Tylenol! I want to emphasize that I think the fear surrounding Tylenol can be a little unnecessary and intense. I do believe there are times Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Reducing the effects of drug toxicity on glutathione metabolism ScienceDirect Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize The Hidden Impact of Acetaminophen Well Rooted What to Avoid When Taking Glutathione Thornhill's Pharmacy