The pentose phosphate pathway in health and disease Nature Metabolism Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Pentose Phosphate Pathway Reactions in Photosynthesizing Cells Pentose Phosphate Pathway ChemTalk HMP also known as the Pentose phosphate pathway. Consists of two irreversible oxidative rxs followed by a series of reversible Frontiers The Role of the Pentose Phosphate Pathway in Diabetes and Cancer