Melanocytic Lesions A Guide to Clinical Differential Diagnosis of Oral Mucosal Lesions Continuing Education Course dentalcare.com Labial melanotic macule Mucosal melanocytic macules Spot the Dot! Growths on the lips are not too common. Clinically, this was consistent with a labial melanotic macule (aka freckle on the lip). These are benign growths which can be Melanotic Macule Lip Removal TikTok This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.