Labial Melanotic Macules DoveMed Labial melanotic macules in atopic dermatitis. (a) Multiple macular Download Scientific Diagram Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) La Bouche Parfaite This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Spot the Dot! Growths on the lips are not too common. Clinically, this was consistent with a labial melanotic macule (aka freckle on the lip). These are benign growths which can be DermDx: Brown Macule on Lip Dermatology Advisor